Dr. Sergey V. Zubkov CURRICULUM VITAE ------------------------------------------------------------------------ Office Address Caseta Technologies, Inc. 30-00 47th ave 5th floor Long Island City, New York, 11101 Office Phone: (718) 349-6799x230 Mobile Phone: (203) 278 0171 (preferred contact) Fax: (516) 208 6657 E-Mail: cubbi@cubbi.com (preferred contact) Education PhD in Chemistry, June 2002 Moscow State University, Department of Chemistry Specialization: Organic Chemistry Master of Science in Chemistry, January 1998 Moscow State University, Department of Material Science Specialization: Organic Chemistry of Materials Bachelor of Science in Material Science, January 1996 Moscow State University, Department of Material Science GPA: 3.94/4.0 Honors and Awards * Personal scholarship of the Moscow State University for gifted young researchers and teachers (2001) * Personal scholarship of the Government of the Russian Federation for gifted graduate students (1999 and 2000) * Medal of graduation with honors from Moscow State University (1998) * Silver Medal in the 24th International Chemistry Olympiad (1992) ------------------------------------------------------------------------ Research Experience Postdoctoral research Stony Brook University, Department of Biochemistry and Cell Biology November 2002 - October 2004 Supervisor: Dr. S. Mohanty Fields of experience: * NMR analysis of proteins: spectral assignment and 3D structure elucidation. * CD and fluorescence chromatography of proteins. * Protein expression in bacteria. * Protein purification (FPLC ion exchange and size exclusion chromatography, SDS PAGE and native protein gels, lyophilization, dialysis) PhD research Moscow State University, Department of Chemistry, NMR laboratory, April 1998 - June 2002 Supervisor: Dr. V. A. Chertkov Fields of experience: * NMR analysis of cyclopentane and cyclohexane derivatives * Design and implementation of a new analysis algorithm for tightly coupled 8- and 9-spin systems. * Precise conformational analysis of cyclopentane derivatives. Jr. Research Scientist State Research Center of Russian Federation: State Scientific Research Institute of Chemistry and Technology of Elementoorganic Compounds, February 1998 - April 1998 Supervisor: Dr. A. Z. Voskoboinikov Fields of experience: * Organic synthesis of cyclopentadiene and dicyclopentane derivatives * and complexes. M.S. research Moscow State University, Department of Chemistry, NMR laboratory, 1996-1998 Supervisor: Dr. V. A. Chertkov Fields of experience: * NMR spectral analysis of small organic molecules * Algorithms of lineshape fitting analysis of complex NMR spectra. (this was continued later in the PhD research) Undergraduate research Moscow State University, Department of Chemistry, NMR Laboratory, 1994-1995 Supervisor: Dr. M. D. Reshetova Fields of experience: * Organic synthesis of nickel - cyclopentadiene complexes ------------------------------------------------------------------------ Professional Service and Volunteer Work * Volunteer part-time biochemistry research associate Stony Brook University, Department of Biochemistry and Cell Biology, November 2004 - December 2005. NMR analysis of proteins: spectral assignment and 3D structure elucidation. * NMR spectrometer maintainance at the NMR Laboratory of the Department of Chemistry, Moscow State University. June 1999 - November 2000 Maintainance of Varian VXR-400 and Bruker DPX-300 spectrometers ------------------------------------------------------------------------ Publications NMR spectroscopy, chemistry, and biochemistry * S.Zubkov, A.M.Gronenborn, I-J.L.Byeon, S.Mohanty, "Structural consequences of the pH-induced conformational switch in A. polyphemus pheromone-binding protein: mechanisms of ligand release", J. Mol. Biol., 2005, 354, 1081-1090. * S.Zubkov, W.J.Lennarz, S.Mohanty, "Structural basis for the function of a minimembrane protein subunit of yeast oligosaccharyltransferase", Proc. Natl. Acad. Sci. USA, 2004, 101, 3821-3826. * S.Mohanty, S.Zubkov, A.M.Gronenborn, "The solution NMR structure of Antheraea polyphemus PBP provides new insight into pheromone recognition by pheronome binding proteins", J. Mol. Biol., 2004, 337, 443-451 * S.Mohanty, S.Zubkov and R.Campos-Olivas, "Letter to the Editor: 1H, 13C, and 15N backbone assignments of the pheromone binding protein from the silk moth Antheraea polyphemus (ApolPBP)", J. Biomol. NMR, 2003, 27, 393-394. * S.V.Zubkov and V.A. Chertkov, "Experimental Determination of Pseudorotation Potentials for Disubstituted Cyclopentanes Based on Spin-Spin Coupling Constants", Int. J. Mol. Sci. 2003, 4, 107-118. * S.V.Zubkov, V.A.Chertkov, S.S.Golotvin, "A new program for total lineshape analysis of NMR spectra. Conformational analysis of trans-1,2-dibromocyclopentane", Russ. Chem. Bull., 2002, 51, N7, 1222-1230. * S.V. Zubkov, S.S. Golotvin, V.A. Chertkov, "New Program VALISA. Conformational Analysis of Some Substituted Cyclopentanes and Cyclohexanes", Russian NMR Newsletter (in Russian), 2000, N1-2, 917-922. * V.A. Chertkov, S.V. Zubkov, A.A. Ovcharenko, A.V. Karchava, M.A. Yurovskaya, "Determination of Ultra Long-Range Spin-Spin Coupling Constants Using Analysis of Full Form of Line in 1H NMR Spectra of Fullerene C60 Cycloadducts with 1-(4-nitrophenyl)-3-phenylnitrililide", Chem. Heterocycl. Compd. (Engl. Transl.), 1999 N11 (389) 1500-1505. * S.V. Zubkov, "Total Lineshape NMR Spectra Analysis", Russian NMR Newsletter (in Russian), 1998, N1, 593-602. * A.V.Makarkina, S.V.Zubkov, V.A.Chertkov, "Orientation of benzothiophene by a magnetic field in the isotropic liquid phase", Chem. Heterocycl. Compd. (Engl. Transl.), 1997, N3 (357), 266-270. Computer science * S.V. Zubkov "Assembler for DOS, Windows and UNIX" - 2nd ed, corr.&add. (in Russian), Moscow, DMK, 2000, 609 pages, ISBN 5-89818-082-6 * S.V. Zubkov. "Linux: Russian versions" (in Russian), 2000, 346 pages, ISBN 5-94074-013-8. * S.V. Zubkov "Assembler for DOS, Windows and UNIX" (in Russian), Moscow, DMK, 1999, 637 pages, ISBN 5-89818-019-2. ------------------------------------------------------------------------ Conference Presentations NMR spectroscopy and chemistry * The 18th Symposium of the Protein Society, La Jolla CA, August 9-20, 2004. S.Mohanty, S.Zubkov, A.M.Gronenborn, "Structural characterization of the Antheraea polyphemus pheromone binding protein in acidic pH" * The 18th Symposium of the Protein Society, La Jolla CA, August 9-20, 2004. S.Mohanty, Z.Nestor, S.Zubkov, M.Maslyanskaya, "Biophysical characterization of the human glutaminase interacting protein containing a PDZ domain and its interaction with C-terminus peptide of glutaminase". * The 17th Symposium of the Protein Society, Boston MA, July 26-30, 2003. Abstract published in: S. Mohanty, S. Zubkov, "NMR Assignment and Secondary Structure of the Silk Moth Antheraea Polyphemus Pheromone Binding Protein ApolPBP", Protein Science, vol 12 suppl 2, 121. * Proceedings of the 15th European Experimental NMR Conference (EENC2000) 12-17 June 2000, University of Leipzig, Germany, p. 42 Abstract published online: http://eenc.uni-leipzig.de/Chertkov.pdf * Proceedings of the III Russian Conference "New achievements of NMR in structural research", 4-7 April 2000. State University of Kazan, Russia, p. 59 (Russian) ------------------------------------------------------------------------ Teaching Experience NMR spectroscopy and chemistry * Instructor of Basic Spectrometer Operation in the NMR laboratory at the Department of Chemistry, Moscow State University. Spring 1998 Computer science * Teacher of Computer Science and Computer Programming at the Department of Material Sciences, Moscow State University. March 2000 - May 2002 ------------------------------------------------------------------------ Computer science experience: NMR/Chemistry related computer science experience: June 1998 - November 2000: UNIX Software developer (part time) The Best Applied NMR, Moscow, Russia. Fully developed three software products: 1. Set of commandline NMR data processing utilities (C, Linux) 2. GUI-driven NMR data processing and spectrum preparation software (C, GTK, Linux) 3. Bruker AU plugins for NMR data processing and editing (C, IRIX) Non-chemical computer science experience: October 2004 - current: Software Developer Caseta Technologies, Inc., Long Island City, NY * Development in C++, Java February 2002 - September 2003: Software Developer Auriga, Inc., Moscow, Russia, contracting at Broadvision, Inc., Redwood City, CA. * Development in C++/MFC November 2000 - January 2002: Continuation Engineer. Auriga, Inc., Moscow, Russia, contracting at LynuxWorks, Inc., San Jose, CA. (6 months working experience in USA) * Investigating defects and implementing fixes and enhancement requests in the operating systems LynxOS (Real Time Embedded OS) and BlueCat (Embedded Linux). Assembly, C, C++ languages, many different platforms and architectures. * Creating new OS patches and service packs * Full OS and patch testing ------------------------------------------------------------------------ Biographical Data Birthdate: February 18, 1976 Place of Birth: Moscow, Russia Citizenship: Russian Work authorization: Authorized to work in the USA for the current employer. ------------------------------------------------------------------------ March 10, 2006, Baldwin NY The online version of this CV is available at http://cubbi.com/cv.txt Please direct reples to cubbi@cubbi.com